PXD015393

PXD015393 is an original dataset announced via ProteomeXchange.

Title	Phosphoproteome profiling unravels rewiring of chromatin organization factors in host cells upon HBV infection
Description	Hepatitis B virus (HBV) infection leads tdevelopment of fatal liver complications. Due to a lack of effective measure to cure HBV infection, complete eradication of HBV is difficult. Thus, novel HBV therapeutic strategies are needed. Host proteins involved in the HBV infection processes are known to be regulated through phosphorylation. System level changes in phospho-signaling pathway in host during infection remains unclear. To this end, phosphoproteome profiling on HBV infected HepG2-NTCP cells was performed.
HostingRepository	PRIDE
AnnounceDate	2022-06-09
AnnouncementXML	Submission_2022-06-09_02:10:50.123.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD015393
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	ZiJie Lim
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Phospho; TMT6plex; Oxidation; Acetyl; Carbamidomethyl
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-09-10 05:44:57	ID requested
⏵ 1	2022-06-09 02:10:50	announced

Lim Z, Mohd-Ismail NKB, Png E, Sze CW, Lin Q, Hong W, Lim SG, Tan YJ, Gunaratne J, Phosphoproteomics Unravel HBV Triggered Rewiring of Host Phosphosignaling Events. Int J Mol Sci, 23(9):(2022) [pubmed]

submitter keyword: Hepatitis B virus, Phosphoproteome, Mass spectrometry, Chromatin remodelling, HBV host response

Jayantha Gunaratne
contact affiliation	Principle Investigator of TBP at IMCB
contact email	jayanthag@imcb.a-star.edu.sg
lab head
ZiJie Lim
contact affiliation	NUS
contact email	mdclimz@nus.edu.sg
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/06/PXD015393

PRIDE project URI

• PRIDE
  1. PXD015393
     1. Label: PRIDE project
     2. Name: Phosphoproteome profiling unravels rewiring of chromatin organization factors in host cells upon HBV infection