PXD015349

PXD015349 is an original dataset announced via ProteomeXchange.

Title	Analysis of the fragments from hTau degraded by proteasome 20s using mass spectrometry
Description	We found two stable intermediates in the interaction of human Tau and proteasome 20s. The aim of this study is to determine the cleavage sites on hTau during this process.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:02:21.914.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pan Fang
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-09-09 00:26:13	ID requested
1	2020-04-21 22:25:29	announced
2	2021-01-06 07:28:02	announced	2021-01-06: Updated publication reference for PubMed record(s): 32832664.
⏵ 3	2024-10-22 05:02:22	announced	2024-10-22: Updated project metadata.

Ukmar-Godec T, Fang P, Ib, á, ñ, ez de Opakua A, Henneberg F, Godec A, Pan KT, Cima-Omori MS, Chari A, Mandelkow E, Urlaub H, Zweckstetter M, Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Sci Adv, 6(30):eaba3916(2020) [pubmed]

10.1126/sciadv.aba3916;

submitter keyword: hTau, mass spectrometry

Henning Urlaub
contact affiliation	Max Planck Institute for biophysical chemistry
contact email	henning.urlaub@mpibpc.mpg.de
lab head
Pan Fang
contact affiliation	Fudan University
contact email	pfang@mpibpc.mpg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/04/PXD015349

PRIDE project URI

• PRIDE
  1. PXD015349
     1. Label: PRIDE project
     2. Name: Analysis of the fragments from hTau degraded by proteasome 20s using mass spectrometry