PXD015242

PXD015242 is an original dataset announced via ProteomeXchange.

Title	Identification of proteins interacted with EphA2 in nasopharyngeal carcinoma cells by LC-MS / MS
Description	To search proteins that interact with EphA2, EphA2 interactors were coimmunoprecipitated with anti-EphA2 antibody from 5-8F NPC cell extracts, separated on SDS-PAGE and stained with Coomassie blue , and non-immune IgG antibody instead of anti-EphA2 antibody served as control. All bands were excised, and subjected to in gel trypsin digestion and liquid chromatography and high-throughput mass spectrometry (LC-MS/MS) analysis.As a result, a total of1352 proteins including ANXA1 and Cbl were identified .
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_13:37:09.103.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shanshan LU
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-30 03:12:02	ID requested
⏵ 1	2021-09-08 13:37:09	announced

Xiang YP, Xiao T, Li QG, Lu SS, Zhu W, Liu YY, Qiu JY, Song ZH, Huang W, Yi H, Tang YY, Xiao ZQ, Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by Shp2/Erk-1/2 signaling pathway. Cell Death Dis, 11(8):709(2020) [pubmed]

submitter keyword: nasopharyngeal carcinoma , EphA2 , LC-MS / MS

Zhi-Qiang Xiao
contact affiliation	Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China
contact email	zqxiao2001@hotmail.com
lab head
Shanshan LU
contact affiliation	Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact email	susan880102@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD015242

PRIDE project URI

• PRIDE
  1. PXD015242
     1. Label: PRIDE project
     2. Name: Identification of proteins interacted with EphA2 in nasopharyngeal carcinoma cells by LC-MS / MS