PXD015126

PXD015126 is an original dataset announced via ProteomeXchange.

Title	MYB-regulated pancreatic cancer secretome
Description	Earlier we have shown important roles of MYB in pancreatic tumor pathobiology. To better understand the role of MYB in the tumor microenvironment and identify MYB-associated secreted biomarker proteins, we conducted mass spectrometry analysis of the secretome from MYB-modulated and control pancreatic cancer cell lines. We also performed in silico analyses to determine MYB-associated biofunctions, gene networks and altered biological pathways. We further investigated the secreted proteins for their potential biomarker properties.
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_11:58:34.773.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ajay Singh
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-22 03:01:46	ID requested
⏵ 1	2021-09-08 11:58:39	announced

Zubair H, Patel GK, Khan MA, Azim S, Zubair A, Singh S, Srivastava SK, Singh AP, Proteomic Analysis of MYB-Regulated Secretome Identifies Functional Pathways and Biomarkers: Potential Pathobiological and Clinical Implications. J Proteome Res, 19(2):794-804(2020) [pubmed]

submitter keyword: pancreatic cancer, MYB, biomarkers, secretome

Dr. Ajay P Singh
contact affiliation	Department of Pathology, University of South Alabama, Mobile, AL
contact email	asingh@health.southalabama.edu
lab head
Ajay Singh
contact affiliation	University of South Alabama
contact email	asingh@health.southalabama.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD015126

PRIDE project URI

• PRIDE
  1. PXD015126
     1. Label: PRIDE project
     2. Name: MYB-regulated pancreatic cancer secretome