PXD015102

PXD015102 is an original dataset announced via ProteomeXchange.

Title	Time-series proteomic study of diabetic nephropathy in human proximal tubular epithelial HK-2 cells
Description	Shotgun time-series proteomic analysis based on stable isotope dimethyl labeling and UHPLC-MS/MSC to relatively quantify the changes in protein expression of human proximal tubular HK-2 cells exposed to a diabetic-like microenvironment
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_13:35:58.869.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alberto Valdés
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	4x(2)H labeled dimethylated residue; acetylated residue; monohydroxylated residue; dimethylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-21 01:00:57	ID requested
⏵ 1	2021-09-08 13:35:59	announced

Vald, é, s A, Castro-Puyana M, Garc, í, a-Pastor C, Lucio-Caza, ñ, a FJ, Marina ML, Time-series proteomic study of the response of HK-2 cells to hyperglycemic, hypoxic diabetic-like milieu. PLoS One, 15(6):e0235118(2020) [pubmed]

submitter keyword: Diabetic nephropathy, HK-2 cells, hyperglycemia, hypoxia, proteomics, proximal tubular cells

María Luisa Marina
contact affiliation	Departamento de Química Analítica, Química Física e Ingeniería Química, Universidad de Alcalá, Ctra. Madrid-Barcelona, Km. 33.600, 28871 Alcalá de Henares, Madrid, España
contact email	mluisa.marina@uah.es
lab head
Alberto Valdés
contact affiliation	Department of Chemistry-BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
contact email	a.valdes@csic.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD015102

PRIDE project URI

• PRIDE
  1. PXD015102
     1. Label: PRIDE project
     2. Name: Time-series proteomic study of diabetic nephropathy in human proximal tubular epithelial HK-2 cells