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PXD014970

PXD014970 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePeptide signature for the fast detection of bacterial species in Urinary Tract infections using LC-MS
DescriptionThe fast identification of microbial species in clinical samples is essential to provide an appropriated antiobiotherapy to the patient and to reduce the prescription of broad spectrum antimicrobials leading to antibioresistances. We have developed a new strategy for the fast identification of bacterial species in urine using a specific peptide signature designed by combination of proteomics data and machine learning approaches. Thereby, we have developed a 82 peptides signature which, we monitored by targeted proteomics, is able to distinguish between the 15 species the most frequently found in Urinary Tract Infections (UTIs). Our method allows the bacterial identification in less than 4 hours without culturing.
HostingRepositoryPanoramaPublic
AnnounceDate2019-10-09
AnnouncementXMLSubmission_2019-10-09_13:55:12.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterClarisse Gotti
SpeciesList scientific name: Klebsiella pneumoniae subsp. pneumoniae MGH 78578; NCBI TaxID: 272620; scientific name: Enterococcus faecalis V583; NCBI TaxID: 226185; scientific name: Streptococcus agalactiae 2603V/R; NCBI TaxID: 208435; scientific name: Escherichia coli K-12; NCBI TaxID: 83333;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion ETD; Q Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-08-09 10:55:49ID requested
12019-10-09 13:55:13announced
Publication List
Roux-Dalvai F, Gotti C, Leclercq M, Hélie MC, Boissinot M, Arrey TN, Dauly C, Fournier F, Kelly I, Marcoux J, Bestman-Smith J, Bergeron MG, Droit A, Fast and Accurate Bacterial Species Identification in Urine Specimens Using LC-MS/MS Mass Spectrometry and Machine Learning. Mol Cell Proteomics, 18(12):2492-2505(2019) [pubmed]
Keyword List
submitter keyword: Bacterial identification
Peptide signature
Urine
Contact List
Arnaud Droit
contact affiliationCHU de Québec - Université Laval research center (Québec, Canada)
contact emailarnaud.droit@crchudequebec.ulaval.ca
lab head
Clarisse Gotti
contact affiliationCHU de Québec - Université Laval research center (Québec, Canada)
contact emailclarisse.gotti@crchudequebec.ulaval.ca
dataset submitter
Full Dataset Link List
Panorama Public dataset URI