PXD014870

PXD014870 is an original dataset announced via ProteomeXchange.

Title	Histone Kla is regulated by cellular glycolysis
Description	We have identified a new histone modification, which is derived from glycolysis end product, lactate. By SILAC-MS/MS based quantification, and U-13C6 glucose labeling experiments, we demonstrate that histone Kla is regulated by cellular glycolysis pathway
HostingRepository	PRIDE
AnnounceDate	2019-10-28
AnnouncementXML	Submission_2019-10-28_01:30:27.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Di Zhang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; isotope labeled residue; 6x(13)C labeled residue; acetylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-01 03:26:30	ID requested
1	2019-08-01 09:10:07	announced
⏵ 2	2019-10-28 01:30:29	announced	2019-10-28: Updated publication reference for PubMed record(s): 31645732.

Zhang D, Tang Z, Huang H, Zhou G, Cui C, Weng Y, Liu W, Kim S, Lee S, Perez-Neut M, Ding J, Czyz D, Hu R, Ye Z, He M, Zheng YG, Shuman HA, Dai L, Ren B, Roeder RG, Becker L, Zhao Y, Metabolic regulation of gene expression by histone lactylation. Nature, 574(7779):575-580(2019) [pubmed]

submitter keyword: Human MCF-7 cells SILAC

Yingming Zhao (Lab Head)
contact affiliation	Ben May department of cancer research, The university of Chicago
contact email	Yingming.Zhao@uchicago.edu
lab head
Di Zhang
contact affiliation	The university of Chicago
contact email	mushiluo@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD014870

PRIDE project URI

• PRIDE
  1. PXD014870
     1. Label: PRIDE project
     2. Name: Histone Kla is regulated by cellular glycolysis