PXD014757

PXD014757 is an original dataset announced via ProteomeXchange.

Title	Quantitative interactome analysis of PHD2
Description	To identify novel regulator of EGLN1/PHD2, we performed label-free quantitative interactome analysis. Stable Hela cell lines expressing Flag-tagged PHD2 and control vector were generated. Immunoprecipitation and mass spectrometry analysis were performed to identify novel interactors of PHD2 followed by validation and functional analysis.
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_11:47:01.449.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yue Chen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-07-25 02:57:10	ID requested
⏵ 1	2021-09-08 11:47:05	announced

Luo A, Chen Y, Label-Free Interactome Analysis Revealed an Essential Role of CUL3-KEAP1 Complex in Mediating the Ubiquitination and Degradation of PHD2. J Proteome Res, 19(1):260-268(2020) [pubmed]

submitter keyword: EGLN1, PHD2, hypoxia, ubiquitination

Yue Chen
contact affiliation	University of Minnesota
contact email	yuechen@umn.edu
lab head
Yue Chen
contact affiliation	University of Minnesota
contact email	ychen2001@yahoo.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD014757

PRIDE project URI

• PRIDE
  1. PXD014757
     1. Label: PRIDE project
     2. Name: Quantitative interactome analysis of PHD2