PXD014503

PXD014503 is an original dataset announced via ProteomeXchange.

Title	PGE2 signaling networks in T cells
Description	We combined phosphoproteomics and phosphoflow cytometry with specific stimulation of the four PGE2 receptors to obtain a global overview of PGE2-regulated signaling pathways and networks in T cells. The study revealed phosphoproteomes regulated uniquely by each receptor and crosstalk between receptors. Previously unknown PGE2-regulated phosphosites were identified, including biologically significant sites.
HostingRepository	PRIDE
AnnounceDate	2022-02-14
AnnouncementXML	Submission_2022-02-14_03:25:09.610.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Piero Giansanti
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion; LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2019-07-05 03:09:48	ID requested
1	2021-08-22 06:09:51	announced
2	2021-10-06 05:11:34	announced	2021-10-06: Updated publication reference for PubMed record(s): 34609894.
⏵ 3	2022-02-14 03:25:10	announced	2022-02-14: Updated project metadata.

Lone AM, Giansanti P, J, ø, rgensen MJ, Gjerga E, Dugourd A, Scholten A, Saez-Rodriguez J, Heck AJR, Task, é, n K, receptors in T cells. Sci Signal, 14(703):eabc8579(2021) [pubmed]

ProteomeXchange project tag: PRIME-XS Project, EPIC-XS

submitter keyword: phosphoflow, T cells, phosphoproteomics, signaling,LC-MSMS

Albert J. R. Heck
contact affiliation	Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands
contact email	A.J.R.Heck@uu.nl
lab head
Piero Giansanti
contact affiliation	Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands
contact email	p.giansanti.uu@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD014503

PRIDE project URI

• PRIDE
  1. PXD014503
     1. Label: PRIDE project
     2. Name: PGE2 signaling networks in T cells