PXD014399

PXD014399 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
Description	To date few DDK substrates other than the MCM helicase have been identified, and none are implicated in fork protection or restart. Here we searched for such factors, using SILAC and quantitative mass spectrometry to identify the DDK phosphoproteome during fork stalling.
HostingRepository	PRIDE
AnnounceDate	2021-06-29
AnnouncementXML	Submission_2021-06-28_21:25:02.372.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Stephanie Munk
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-26 05:42:16	ID requested
⏵ 1	2021-06-28 21:25:03	announced

Publication List

Jones MJK, Gelot C, Munk S, Koren A, Kawasoe Y, George KA, Santos RE, Olsen JV, McCarroll SA, Frattini MG, Takahashi TS, Jallepalli PV, Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. Mol Cell, 81(3):426-441.e8(2021) [pubmed]

Jones MJK, Gelot C, Munk S, Koren A, Kawasoe Y, George KA, Santos RE, Olsen JV, McCarroll SA, Frattini MG, Takahashi TS, Jallepalli PV, Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. Mol Cell, 81(3):426-441.e8(2021) [pubmed]

Keyword List

submitter keyword: LC-MS/MS, chemical genetics, cdc7, DDK, stalled forks, analogue-sesitive, phosphoproteomics, replication

submitter keyword: LC-MS/MS, chemical genetics, cdc7, DDK, stalled forks, analogue-sesitive, phosphoproteomics, replication

Contact List

Prasad Jallepalli
contact affiliation	Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
contact email	jallepap@mskcc.org
lab head
Stephanie Munk
contact affiliation	Copenhagen University
contact email	steph.munk@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/06/PXD014399
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/06/PXD014399

PRIDE project URI

Repository Record List

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