PXD014374

PXD014374 is an original dataset announced via ProteomeXchange.

Title	Proteomic assessments of muscle tissues in cattle that are diet restricted and subsequently undergo compensatory growth
Description	Compensatory growth is a naturally occurring accelerated growth phenomenon observed in cattle upon re-alimentation following a prior period of dietary restriction (Hornick et al., 2000). It is incorporated into man production systems as a method to reduce feed costs and consequently is economically important for animal production systems. The goal of our research project is to identify biomarkers for cattle with a superior ability to display compensatory growth. Transcriptional profiling studies of liver and muscle tissues in cattle have shown large numbers of differentially expressed genes in animals undergoing dietary restriction and subsequent compensatory growth when compared to a continuously-fed ad libitum control group of cattle (Connor et al., 2010; Keogh et al., 2016a,b). Given the identification of differential expression at the transcript level, the intended project aims to evaluate potential differences in protein abundance between animals that are diet restricted and subsequently undergo compensatory growth compared to a continuously-fed ad libitum control group of cattle. Differences in genes that are apparent at both the protein and the transcript level are more likely to be transferable across breed type (Snelling et al., 2013) and consequently have more utility for incorporation within genomic selection breeding programs for cattle evaluations.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:11:51.911.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yvonne Mullins
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-25 02:20:51	ID requested
1	2020-02-18 06:29:43	announced
⏵ 2	2024-10-22 04:11:57	announced	2024-10-22: Updated project metadata.

Mullins Y, Keogh K, Kenny DA, Kelly A, O' Boyle P, Waters SM, Label-free quantitative proteomic analysis of M. longissimus dorsi from cattle during dietary restriction and subsequent compensatory growth. Sci Rep, 10(1):2613(2020) [pubmed]

10.1038/s41598-020-59412-6;

submitter keyword: Bovine, Compensatory growth, LC/MS-MS

Dr. Sinead Waters
contact affiliation	Animal Bioscience Department, Teagasc
contact email	sinead.waters@teagasc.ie
lab head
Yvonne Mullins
contact affiliation	Teagasc Grange
contact email	yvonne.mullins@teagasc.ie
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/02/PXD014374

PRIDE project URI

• PRIDE
  1. PXD014374
     1. Label: PRIDE project
     2. Name: Proteomic assessments of muscle tissues in cattle that are diet restricted and subsequently undergo compensatory growth