PXD014356

PXD014356 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysi of decellularized porcine pancreas
Description	The extracellular matrix is an important part of the cellular microenvironment regulating various cellular functions. Decellularized matrices present a valuable strategy for recreating the cellular niche in vitro and implementing matrix signaling in cell culture models. However, the tissue-specificity of decellularized matrices is little considered in most in vitro models. Here, we present the generation of a porcine-derived pancreas-specific decellularized extracellular matrix scaffold (d-PanMa) and show the impact of scaffold-specific cues on stem cell culture. The proteomic analysis in this work compare the proteome of porcine pancreas (PanMa), intestine (SISser) and lung (lungMa) both in its native and decellularized form. The analysis verify the enrichment of important matrisome proteins in the decellular matrices and provide a detailed map of the protein composition and abundance across the matrices.
HostingRepository	PRIDE
AnnounceDate	2020-03-23
AnnouncementXML	Submission_2020-03-23_00:25:10.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yngvild Bjørlykke
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-24 03:59:02	ID requested
⏵ 1	2020-03-23 00:25:12	announced

Berger C, Bj, ø, rlykke Y, Hahn L, M, ü, hlemann M, Kress S, Walles H, Luxenhofer R, R, æ, der H, Metzger M, Zdzieblo D, Matrix decoded - A pancreatic extracellular matrix with organ specific cues guiding human iPSC differentiation. Biomaterials, 244():119766(2020) [pubmed]

submitter keyword: Porcine, pancreas, LC-MSMS

Helge Ræder
contact affiliation	Department of Clinical Science, Haukeland university hospital, Norway
contact email	helge.rader@uib.no
lab head
Yngvild Bjørlykke
contact affiliation	University of Bergen
contact email	yngvild.bjorlykke@uib.no
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/03/PXD014356

PRIDE project URI

• PRIDE
  1. PXD014356
     1. Label: PRIDE project
     2. Name: Proteomic analysi of decellularized porcine pancreas