PXD014352

PXD014352 is an original dataset announced via ProteomeXchange.

Title	Tissue Proteome Profiling of Ovarian cancer.
Description	Ovarian cancer is one of the leading causes of death from cancer in females, worldwide. An early diagnosis of ovarian carcinoma is likely to improve clinical outcome of patients in terms of reduced morbidity and mortality. The objective of our project is the proteomic analysis of ovarian malignant and non-malignant tissue samples to find potential biomarkers of disease diagnosis and prognosis that can be assessed non-invasively through patient plasma/serum screening. In this project, we have used a methodical approach involving 2-dimensional gel electrophoresis in conjunction with MALDI-TOF MS analysis followed by immunological validation of the selected markers by western blotting and ELISA for identification of biomarkers of ovarian cancer. The associated research paper is in preparation.
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_09:55:07.481.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Muhammad Akhtar
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	ultraflex

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-24 03:21:38	ID requested
⏵ 1	2021-09-08 09:55:08	announced

Noreen S, Akhtar S, Batool T, Gardner QA, Akhtar MW, Tubulin Beta 2C Chain (TBB2C), a Potential Marker of Ovarian Cancer, an Insight from Ovarian Cancer Proteome Profile. ACS Omega, 6(16):10506-10514(2021) [pubmed]

submitter keyword: Mass spectrometry, Proteome profiling, 2D-PAGE, Ovarian cancer, Western blotting, ELISA

Prof. Dr. M. Waheed Akhtar
contact affiliation	Prof. Dr. M. Waheed Akhtar, School of Biological Sciences, University of the Punjab, Lahore, Pakistan
contact email	mwa.sbs@pu.edu.pk
lab head
Muhammad Akhtar
contact affiliation	School of Biological Sciences, University of the Punjab, Lahore, Pakistan
contact email	mwa.sbs@pu.edu.pk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD014352

PRIDE project URI

• PRIDE
  1. PXD014352
     1. Label: PRIDE project
     2. Name: Tissue Proteome Profiling of Ovarian cancer.