PXD014342

PXD014342 is an original dataset announced via ProteomeXchange.

Title	A Pleistocene hominin enamel proteome from Homo antecessor
Description	Hominin relationships and their dispersal throughout Eurasia during the Early and Middle Pleistocene are highly debated. The relationships between Early and Middle Pleistocene hominins, like Homo antecessor and Homo erectus, and hominin species that dominate the Late Pleistocene fossil record, like Homo sapiens, Neanderthals and Denisovans, are unclear. Here, we obtain enamel proteomes from Homo antecessor (Atapuerca, Spain) and Homo erectus (Dmanisi, Georgia), two key fossil assemblages that have a central role in models of Pleistocene hominin morphology, dispersal, and divergence. We recover endogenous ancient proteomes from the Atapuerca and Dmanisi hominins. In addition, our proteomic data indicates that the sampled Homo antecessor molar derives from a male hominin through amelogenin protein sexing. Our data includes preserved in vivo phosphorylation and enamel proteome proteolytic digestion.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:01:37.184.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frido Welker
SpeciesList	scientific name: Homo; NCBI TaxID: 9605;
ModificationList	dihydroxylated residue; hydroxylated residue; phosphorylated residue; monohydroxylated residue; deamidated residue
Instrument	Orbitrap Fusion Lumos; Q Exactive HF; Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-21 04:05:27	ID requested
1	2020-04-01 22:23:09	announced
2	2020-04-13 22:27:11	announced	2020-04-14: Updated publication reference for PubMed record(s): 32269345.
⏵ 3	2024-10-22 05:01:38	announced	2024-10-22: Updated project metadata.

Welker F, Ramos-Madrigal J, Gutenbrunner P, Mackie M, Tiwary S, Rakownikow Jersie-Christensen R, Chiva C, Dickinson MR, Kuhlwilm M, de Manuel M, Gelabert P, Martin, ó, n-Torres M, Margvelashvili A, Arsuaga JL, Carbonell E, Marques-Bonet T, Penkman K, Sabid, ó E, Cox J, Olsen JV, Lordkipanidze D, Racimo F, Lalueza-Fox C, Berm, ú, dez de Castro JM, Willerslev E, Cappellini E, The dental proteome of Homo antecessor. Nature, 580(7802):235-238(2020) [pubmed]

10.1038/s41586-020-2153-8;

submitter keyword: enamel, hominins, phosphorylation,Palaeoproteomics, LC-MS/MS

Enrico Cappellini
contact affiliation	University of Copenhagen
contact email	ecappellini@ku.dk
lab head
Frido Welker
contact affiliation	Postdoc Department of Biology, University of Copenhagen
contact email	frido.welker@palaeo.eu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/04/PXD014342

PRIDE project URI

• PRIDE
  1. PXD014342
     1. Label: PRIDE project
     2. Name: A Pleistocene hominin enamel proteome from Homo antecessor