<<< Full experiment listing


PXD014337 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA synthetic crosslinked peptide library for benchmarking crosslinking mass spectrometry search engines
DescriptionWe have created a synthetic crosslinked peptide library to benchmark crosslinking mass spectrometry search engines. The unique benefit of the library is knowing which identified crosslinks are true and which are false. The data collected from mass spectrometry measurements of the peptide library were used to assess the most frequently used search algorithms. The datasets included will provide an important resource for the crosslinking community to evaluate and optimise search engines, results from which have far-reaching implications.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRebecca Beveridge
SpeciesList scientific name: Streptococcus pyogenes ABC020006030; NCBI TaxID: 1438992;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos; Q Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-06-21 03:36:53ID requested
12019-11-21 01:43:33announced
22020-02-17 03:21:16announced2020-02-17: Updated publication reference for PubMed record(s): 32029734.
32020-11-06 08:30:41announced2020-11-06: Updated project metadata.
Publication List
Beveridge R, Stadlmann J, Penninger JM, Mechtler K, A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes. Nat Commun, 11(1):742(2020) [pubmed]
Keyword List
ProteomeXchange project tag: EPIC-XS
submitter keyword: crosslinking mass spectrometry peptide library
Contact List
Karl Mechtler
contact affiliationInstitute for Molecular Pathology, Vienna, Austria. Institute of Molecular Biotechnology, Vienna Austria
contact emailkarl.mechtler@imp.ac.at
lab head
Rebecca Beveridge
contact affiliationInstitute for Molecular Pathology
contact emailrebecca.beveridge@imp.ac.at
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
[ + ]