PXD014177

PXD014177 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of Mycobacterium tuberculosis induced by rifampicim
Description	Rifampicin plays an important role during tuberculosis treatment, which historically contributed for shortening therapy; however, rifampicin resistance has been the intersection for the definition of multi (MDR-TB) and extensively (XDR-TB) resistant outcomes. A key aspect which has contributed for investigations of drug action/resistance is the understanding of the dynamic genome expression, as that analyzed by Proteomics. Proteins from the reference strain, Mycobacterium tuberculosis H37Rv were extracted after 12, 24 and 48 hours over rifampicin challenge at the minimal inhibitory concentration (0.03 μg•mL-1) and identified by LC-MS.
HostingRepository	PRIDE
AnnounceDate	2021-05-05
AnnouncementXML	Submission_2021-05-04_22:20:57.760.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jean Eduardo Meneguello
SpeciesList	scientific name: Mycobacterium tuberculosis H37Rv; NCBI TaxID: 83332;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	impact II

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-07 05:08:47	ID requested
1	2021-05-04 05:41:23	announced
⏵ 2	2021-05-04 22:20:58	announced	2021-05-05: Updated project metadata.

Meneguello JE, Arita GS, Silva JVO, Ghiraldi-Lopes LD, Caleffi-Ferracioli KR, Siqueira VLD, Scodro RBL, Pilau EJ, Campanerut-S, á PAZ, Cardoso RF, Insight about cell wall remodulation triggered by rifampicin in Mycobacterium tuberculosis. Tuberculosis (Edinb), 120():101903(2020) [pubmed]

10.1016/J.TUBE.2020.101903;

submitter keyword: Mycobacterium tuberculosis,proteomics, drug resistance, cell wall

Paula Aline Zanetti Campanerut-Sá
contact affiliation	Postgraduate Program in Health Sciences, Center of Health Sciences, State University of Maringá, Maringá-PR, Brazil
contact email	paulacampanerut@gmail.com
lab head
Jean Eduardo Meneguello
contact affiliation	State University of Maringá
contact email	meneguello.je@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/05/PXD014177

PRIDE project URI

• PRIDE
  1. PXD014177
     1. Label: PRIDE project
     2. Name: Proteomic analysis of Mycobacterium tuberculosis induced by rifampicim