PXD014138

PXD014138 is an original dataset announced via ProteomeXchange.

Title	Age-dependent dynamics of ribosomal proteins in mouse brain
Description	To determine the dynamics of ribosomal proteins in brain tissues, we isolated monoribosomes and ribosomes engaged in polysomal fractions from three different brain tissues, cerebellum, hippocampus and cortex, and compared them to the liver of CD-1 IGS mouse. We provide a comprehensive unique study of the ribosomal composition among these different tissues along different life stages, from juvenile (three-weeks), young adult (four-months) to mature adults (seven- and twelve-months) of age. The protein composition of the ribosomes was quantified using LC-MS/MS approach.
HostingRepository	PRIDE
AnnounceDate	2019-10-10
AnnouncementXML	Submission_2019-10-25_04:12:46.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christoph Krisp
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-05 04:16:39	ID requested
1	2019-10-10 04:00:22	announced
⏵ 2	2019-10-25 04:12:48	announced	2019-10-25: Updated publication reference for PubMed record(s): 31636180.

Amirbeigiarab S, Kiani P, Velazquez Sanchez A, Krisp C, Kazantsev A, Fester L, Schl, ü, ter H, Ignatova Z, Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. Proc Natl Acad Sci U S A, 116(45):22567-22572(2019) [pubmed]

curator keyword: Biological

submitter keyword: ribosomal proteins

translation

age-dependent changes

mouse brain tissues

mass spectrometry

Zoya Ignatova
contact affiliation	Biochemistry and Molecular Biology Department of Chemistry University of Hamburg, Hamburg, Germany
contact email	zoya.ignatova@uni-hamburg.de
lab head
Christoph Krisp
contact affiliation	University Medical Center Hamburg-Eppendorf Institute of Clinical Chemistry and Laboratory Medicine Mass Spectrometric Proteomics
contact email	c.krisp@uke.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD014138

PRIDE project URI

• PRIDE
  1. PXD014138
     1. Label: PRIDE project
     2. Name: Age-dependent dynamics of ribosomal proteins in mouse brain