PXD014131 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human liver homogenate, liver microsomes, low-speed centrifugation pellet and hepatocytes LC-MS/MS from 15 matched donors |
Description | LC-MS/MS-based label-free proteomics of human liver homogenate, human liver microsomes, and human hepatocytes from 15 matched donors used to compare and understand differences in two major in vitro systems used for drug metabolism studies |
HostingRepository | PRIDE |
AnnounceDate | 2021-03-29 |
AnnouncementXML | Submission_2021-03-29_00:33:04.804.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Christine Wegler |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-06-05 01:54:28 | ID requested | |
⏵ 1 | 2021-03-29 00:33:05 | announced | |
Publication List
Wegler C, Matsson P, Krogstad V, Urdzik J, Christensen H, Andersson TB, Artursson P, Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes. Mol Pharm, 18(4):1792-1805(2021) [pubmed] |
Keyword List
submitter keyword: Human, Liver, Liver microsomes, Low-speed centrifugation pellet, Hepatocytes, LC-MS/MS |
Contact List
Per Artursson |
contact affiliation | Department of Pharmacy, Uppsala University |
contact email | per.artursson@farmaci.uu.se |
lab head | |
Christine Wegler |
contact affiliation | Uppsala University |
contact email | christine.wegler@farmaci.uu.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD014131 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD014131
- Label: PRIDE project
- Name: Human liver homogenate, liver microsomes, low-speed centrifugation pellet and hepatocytes LC-MS/MS from 15 matched donors