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PXD014131

PXD014131 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman liver homogenate, liver microsomes, low-speed centrifugation pellet and hepatocytes LC-MS/MS from 15 matched donors
DescriptionLC-MS/MS-based label-free proteomics of human liver homogenate, human liver microsomes, and human hepatocytes from 15 matched donors used to compare and understand differences in two major in vitro systems used for drug metabolism studies
HostingRepositoryPRIDE
AnnounceDate2021-03-29
AnnouncementXMLSubmission_2021-03-29_00:33:04.804.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChristine Wegler
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-06-05 01:54:28ID requested
12021-03-29 00:33:05announced
Publication List
Wegler C, Matsson P, Krogstad V, Urdzik J, Christensen H, Andersson TB, Artursson P, Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes. Mol Pharm, 18(4):1792-1805(2021) [pubmed]
Keyword List
submitter keyword: Human, Liver, Liver microsomes, Low-speed centrifugation pellet, Hepatocytes, LC-MS/MS
Contact List
Per Artursson
contact affiliationDepartment of Pharmacy, Uppsala University
contact emailper.artursson@farmaci.uu.se
lab head
Christine Wegler
contact affiliationUppsala University
contact emailchristine.wegler@farmaci.uu.se
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
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