PXD014061

PXD014061 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Expression of Ciona intestinalis alternative oxidase (AOX) in a mouse model of cardiac ischemia-reperfusion
Description	The objective of this study was to test how restoration of mitochondrial respiration using AOX affects the development of cardiac ischemia-reperfusion (IR) injuries in C57BL/ 6J mice. AOX transgenic mice have Ciona intestinalis AOX coding sequence knocked into the Rosa26 locus with AOX expression controlled by a CAG promoter as described elsewhere (Szibor et al. (2017) Dis Model Mech 10: 163–171). Consequences of 45 min of cardiac ischemia were studied 3 and 9 weeks after reperfusion in both wild-type and AOX litter mates.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:54:16.019.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tuula Nyman
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-05-29 03:59:53	ID requested
1	2020-01-30 02:30:36	announced
2	2020-02-18 07:40:28	announced	2020-02-18: Updated publication reference for PubMed record(s): 32040259.
⏵ 3	2024-10-22 04:54:19	announced	2024-10-22: Updated project metadata.

Publication List

10.1111/jcmm.15043;
Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, G, ä, rtner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, Braun T, Gellerich FN, Schl, ü, ter KD, Jacobs HT, Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia. J Cell Mol Med, 24(6):3534-3548(2020) [pubmed]

10.1111/jcmm.15043;

Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, G, ä, rtner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, Braun T, Gellerich FN, Schl, ü, ter KD, Jacobs HT, Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia. J Cell Mol Med, 24(6):3534-3548(2020) [pubmed]

Keyword List

submitter keyword: mitochondrial respiration, mitochondrial electron transport chain (ETC),mitochondria, alternative oxidase (AOX), cardiac ischemia-reperfusion

submitter keyword: mitochondrial respiration, mitochondrial electron transport chain (ETC),mitochondria, alternative oxidase (AOX), cardiac ischemia-reperfusion

Contact List

Tuula Nyman
contact affiliation	Head of Proteomics
contact email	tuula.nyman@medisin.uio.no
lab head
Tuula Nyman
contact affiliation	University of Oslo
contact email	tuula.nyman@medisin.uio.no
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/01/PXD014061
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/01/PXD014061

PRIDE project URI

Repository Record List

[ + ]