PXD014046

PXD014046 is an original dataset announced via ProteomeXchange.

Title	The acetylome analysis of lysine acetylation in the plant pathogenic bacterium Brenneria nigrifluens
Description	Protein lysine acetylation, a dynamic and reversible posttranslational modification, plays a crucial role in several cellular processes including cell cycle regulation, metabolic pathways, enzymatic activities and protein interactions. Brenneria nigrifluens is the pathogen of shallow bark canker of walnut trees and can cause serious disease on walnut trees. Up to now, it is little known about the roles of lysine acetylation in the plant pathogenic bacteria. In the present study, the lysine acetylome of B. nigrifluens was determined by high-resolution LC-MS/MS analysis. In total, we identified 1,866 lysine acetylation sites distributed in 737 acetylated proteins. Bioinformatics results indicate that acetylated proteins participate in many different biological functions in B. nigrifluens. Four conserved motifs, namely, LKac, Kac*F, I*Kac and L*Kac, were identified in this bacterium. Protein interaction network analysis indicates that all kinds of interactions are modulated by protein lysine acetylation. Overall, 14 acetylated proteins are related to the virulence of B. nigrifluens.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:55:43.854.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yong Li
SpeciesList	scientific name: Bacteria; NCBI TaxID: NCBITaxon:2; scientific name: Brenneria nigrifluens; NCBI TaxID: 55210;
ModificationList	acetylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-05-28 05:53:49	ID requested
1	2019-09-30 01:38:49	announced
⏵ 2	2024-10-22 04:55:44	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Brenneria nigrifluens,LC-MSMS, plant pathogen

Yong Li
contact affiliation	Research Institute of Forest Ecology Environment and Protection, Chinese Academy of Forestry
contact email	lylx78@hotmail.com
lab head
Yong Li
contact affiliation	Research Institute of Forest Ecology Environment and Protection
contact email	lylx78@hotmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD014046
     1. Label: PRIDE project
     2. Name: The acetylome analysis of lysine acetylation in the plant pathogenic bacterium Brenneria nigrifluens