PXD013953 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Comparative integrated omics analysis of the Hfq regulon in Bordetella pertussis |
Description | This study represents the first attempt to characterize the RNA chaperone Hfq regulon in bacterial pathogen using an integrative omics approach. Gene expression profiles were analyzed by RNA-seq and protein amounts in cell-associated and cell-free fractions were determined by LC-MS/MS technique. Comparative analysis of transcriptomic and proteomic data revealed solid correlation considering the role of Hfq in post-transcriptional control of gene expression. Importantly, our study confirms and further enlightens the role of Hfq in pathogenicity of B. pertussis. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:55:18.624.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Denisa Petrackova |
SpeciesList | scientific name: Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251); NCBI TaxID: 257313; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-05-21 05:24:47 | ID requested | |
1 | 2019-07-02 05:57:35 | announced | |
⏵ 2 | 2024-10-22 04:55:20 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dienstbier A, Amman F, Š, tipl D, Petr, á, č, kov, á D, Ve, č, erek B, . Int J Mol Sci, 20(12):(2019) [pubmed] |
10.3390/ijms20123073; |
Keyword List
submitter keyword: hfq regulon, LFQ MS,Bordetella pertussis |
Contact List
Branislav Vecerek |
contact affiliation | Laboratory of Post-Transcriptional Control of Gene Expression Institute of Microbiology, v.v.i. Academy of Sciences of the Czech Republic Videnska 1083; Prague; Czech Republic Tel: +420 296 442 507 |
contact email | vecerek@biomed.cas.cz |
lab head | |
Denisa Petrackova |
contact affiliation | Institute of Microbiology of the CAS, v. v. i. |
contact email | petrack@biomed.cas.cz |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD013953
- Label: PRIDE project
- Name: Comparative integrated omics analysis of the Hfq regulon in Bordetella pertussis