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PXD013953

PXD013953 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComparative integrated omics analysis of the Hfq regulon in Bordetella pertussis
DescriptionThis study represents the first attempt to characterize the RNA chaperone Hfq regulon in bacterial pathogen using an integrative omics approach. Gene expression profiles were analyzed by RNA-seq and protein amounts in cell-associated and cell-free fractions were determined by LC-MS/MS technique. Comparative analysis of transcriptomic and proteomic data revealed solid correlation considering the role of Hfq in post-transcriptional control of gene expression. Importantly, our study confirms and further enlightens the role of Hfq in pathogenicity of B. pertussis.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:55:18.624.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDenisa Petrackova
SpeciesList scientific name: Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251); NCBI TaxID: 257313;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-05-21 05:24:47ID requested
12019-07-02 05:57:35announced
22024-10-22 04:55:20announced2024-10-22: Updated project metadata.
Publication List
Dienstbier A, Amman F, Š, tipl D, Petr, á, č, kov, á D, Ve, č, erek B, . Int J Mol Sci, 20(12):(2019) [pubmed]
10.3390/ijms20123073;
Keyword List
submitter keyword: hfq regulon, LFQ MS,Bordetella pertussis
Contact List
Branislav Vecerek
contact affiliationLaboratory of Post-Transcriptional Control of Gene Expression Institute of Microbiology, v.v.i. Academy of Sciences of the Czech Republic Videnska 1083; Prague; Czech Republic Tel: +420 296 442 507
contact emailvecerek@biomed.cas.cz
lab head
Denisa Petrackova
contact affiliationInstitute of Microbiology of the CAS, v. v. i.
contact emailpetrack@biomed.cas.cz
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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