PXD013937

PXD013937 is an original dataset announced via ProteomeXchange.

Title	Proteome of follicular Fluid from lean and overweight/obese women with PCOS and that of healthy controls
Description	Polycystic ovary syndrome (PCOS) is typically characterized by oligo or anovulation, hyperandrogenism and polycystic ovarian morphology, affecting 5-20% of women of reproductive age [1]. It has drawn significant attention as a major cause of anovulatory infertility and the syndrome of metabolic, reproductive and obstetrical disorders [2 ,+]. Due to heterogeneous clinical features and unclear pathogenesis of PCOS, the diagnosis and treatment strategies remain a matter of debate. To better understand the complex follicular development environment in PCOS, we conducted a TMT-based quantitative proteomic study to compare the composition of proteins, pathways and molecular functions of FF from lean and overweight/obese women with PCOS and that of healthy controls.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:56:50.271.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mengwei Wu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-05-20 06:58:37	ID requested
1	2019-10-31 08:10:30	announced
⏵ 2	2024-10-22 04:56:50	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Human,PCOS, TMT

Zhang Xinyi
contact affiliation	Shengjing Hospital of China medical University
contact email	466818142@qq.com
lab head
Mengwei Wu
contact affiliation	shengjing hospital of China medical University
contact email	466818142@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD013937

PRIDE project URI

• PRIDE
  1. PXD013937
     1. Label: PRIDE project
     2. Name: Proteome of follicular Fluid from lean and overweight/obese women with PCOS and that of healthy controls