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PXD013855

PXD013855 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRole of GATA-2 -77 enhancer in murine blood progenitor cells
DescriptionWe discovered enhancers that control GATA-2 expression during mouse development and in adult and generated mutant mouse strains that lack these enhancers, and these mice have very specific and important phenotypes that revealed GATA-2 mechanisms to control stem and progenitor cell transitions. In this study we aim to determine what proteins are under control of the GATA-2 -77 enhancer in a pool of heterogeneous blood progenitor cells with the specific focus on Socs2 expression.
HostingRepositoryPRIDE
AnnounceDate2020-06-05
AnnouncementXMLSubmission_2020-08-04_23:13:50.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEvgenia Shishkova
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-05-15 03:23:50ID requested
12020-06-04 22:51:46announced
22020-08-04 23:13:51announced2020-08-05: Updated publication reference for PubMed record(s): 32736380.
Publication List
Johnson KD, Conn DJ, Shishkova E, Katsumura KR, Liu P, Shen S, Ranheim EA, Kraus SG, Wang W, Calvo KR, Hsu AP, Holland SM, Coon JJ, Keles S, Bresnick EH, Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories. J Exp Med, 217(11):(2020) [pubmed]
Keyword List
submitter keyword: label-free proteomics, primary tissue, targeted proteomics, deep analysis
Contact List
Joshua Coon
contact affiliationUniversity of Wisconsin - Madison
contact emailjcoon@chem.wisc.edu
lab head
Evgenia Shishkova
contact affiliationUniversity of Wisconsin - Madison
contact emailshishkova@wisc.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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