PXD013855 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Role of GATA-2 -77 enhancer in murine blood progenitor cells |
Description | We discovered enhancers that control GATA-2 expression during mouse development and in adult and generated mutant mouse strains that lack these enhancers, and these mice have very specific and important phenotypes that revealed GATA-2 mechanisms to control stem and progenitor cell transitions. In this study we aim to determine what proteins are under control of the GATA-2 -77 enhancer in a pool of heterogeneous blood progenitor cells with the specific focus on Socs2 expression. |
HostingRepository | PRIDE |
AnnounceDate | 2020-06-05 |
AnnouncementXML | Submission_2020-08-04_23:13:50.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Evgenia Shishkova |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-05-15 03:23:50 | ID requested | |
1 | 2020-06-04 22:51:46 | announced | |
⏵ 2 | 2020-08-04 23:13:51 | announced | 2020-08-05: Updated publication reference for PubMed record(s): 32736380. |
Publication List
Johnson KD, Conn DJ, Shishkova E, Katsumura KR, Liu P, Shen S, Ranheim EA, Kraus SG, Wang W, Calvo KR, Hsu AP, Holland SM, Coon JJ, Keles S, Bresnick EH, Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories. J Exp Med, 217(11):(2020) [pubmed] |
Keyword List
submitter keyword: label-free proteomics, primary tissue, targeted proteomics, deep analysis |
Contact List
Joshua Coon |
contact affiliation | University of Wisconsin - Madison |
contact email | jcoon@chem.wisc.edu |
lab head | |
Evgenia Shishkova |
contact affiliation | University of Wisconsin - Madison |
contact email | shishkova@wisc.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD013855 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD013855
- Label: PRIDE project
- Name: Role of GATA-2 -77 enhancer in murine blood progenitor cells