PXD013767

PXD013767 is an original dataset announced via ProteomeXchange.

Title	Mass spectrometry of excretory/secretory products (ectosomes, exosomes, and soluble proteins) secreted by Toxoplasma gondii tachyzoites isolated from an infected murine model.
Description	Toxoplasma gondii is an intracellular parasite that infects all nucleated cells; to date, this organism is considered as one of the most successful parasites in the world. During infection, internalization, and proliferation the parasite excretes/secretes a high number of proteins, several of them with identified roles, including MIC proteins, ROP proteins and GRA proteins involved in adhesion, invasion and intracellular proliferation respectively. The characterization of the secretome of Toxoplasma gondii opens the possibility to find new molecules for the design of future anti-parasitic strategies. The complete secretome and proteome of the parasite isolated from the murine model as well as their quantification by MS analysis are now available in the present report.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:50:13.957.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Emmanuel Rios-Castro
SpeciesList	scientific name: Toxoplasma gondii GT1; NCBI TaxID: 507601;
ModificationList	amidated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2019-05-08 04:25:10	ID requested
1	2019-08-29 06:12:36	announced
2	2019-08-29 07:47:14	announced	Updated publication reference for PubMed record(s): 31434009.
⏵ 3	2023-11-14 08:50:17	announced	2023-11-14: Updated project metadata.

Ram, í, rez-Flores CJ, Cruz-Mir, ó, n R, Mondrag, ó, n-Castel, á, n ME, Gonz, á, lez-Pozos S, R, í, os-Castro E, Mondrag, ó, n-Flores R, Proteomic and structural characterization of self-assembled vesicles from excretion/secretion products of Toxoplasma gondii. J Proteomics, 208():103490(2019) [pubmed]

submitter keyword: Toxoplasma gondii., Quantification, Excretory/secretory products, Mass spectrometry,Ectosomes, Exosomes

Ricardo Mondragón-Flores
contact affiliation	Department of Biochemistry, Cinvestav-IPN.
contact email	rmflores@cinvestav.mx
lab head
Emmanuel Rios-Castro
contact affiliation	Cinvestav-IPN
contact email	eriosc@cinvestav.mx
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD013767

PRIDE project URI

• PRIDE
  1. PXD013767
     1. Label: PRIDE project
     2. Name: Mass spectrometry of excretory/secretory products (ectosomes, exosomes, and soluble proteins) secreted by Toxoplasma gondii tachyzoites isolated from an infected murine model.