PXD013690

PXD013690 is an original dataset announced via ProteomeXchange.

Title	Dynamic metabolic reprogramming in dendritic cells: an early response to influenza infection that is essential for effector function
Description	In response to influenza infection we found that dendritic cells (DCs), cells that are critical in mounting an effective immune response, undergo a profound metabolic shift. DCs alter the concentration and location of hundreds of proteins, including c-MYC, mediating a shift to a highly glycolytic phenotype that is also flexible in terms of fueling respiration.
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_09:54:26.249.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Matthew Monroe
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2019-05-02 01:33:49	ID requested
⏵ 1	2021-09-08 09:54:26	announced

Rezinciuc S, Bezavada L, Bahadoran A, Duan S, Wang R, Lopez-Ferrer D, Finkelstein D, McGargill MA, Green DR, Pasa-Tolic L, Smallwood HS, Dynamic metabolic reprogramming in dendritic cells: An early response to influenza infection that is essential for effector function. PLoS Pathog, 16(10):e1008957(2020) [pubmed]

submitter keyword: Metabolism, Influenza, Dendritic Cells

Heather Smallwood
contact affiliation	Pacific Northwest National Laboratory
contact email	hsmallwo@uthsc.edu
lab head
Matthew Monroe
contact affiliation	Pacific Northwest National Laboratory, USA
contact email	matthew.monroe@pnnl.gov
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD013690

PRIDE project URI

• PRIDE
  1. PXD013690
     1. Label: PRIDE project
     2. Name: Dynamic metabolic reprogramming in dendritic cells: an early response to influenza infection that is essential for effector function