PXD013683 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of histone adducts with glycidamide |
Description | Identification of protein covalent modifications (adducts) is a challenging task mainly due to the lack of data processing approaches for Adductomics studies. We report a novel strategy to identify covalently modified peptides that consists on LC-MS data preprocessing followed by statistical analysis. This strategy was compared with the standard methodology of adductomics, which relies on producing comprehensive MS/MS data by data dependent acquisition and analysis with proteomics data search engines (Mascot, Global Proteome Machine interface (GPM Fury) that uses X!Tandem, MaxQuant and MSFragger). |
HostingRepository | PRIDE |
AnnounceDate | 2019-07-25 |
AnnouncementXML | Submission_2019-08-22_01:34:32.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD013683 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Judit Morello |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Oxidation; Glycidamide |
Instrument | impact II |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-05-01 05:55:42 | ID requested | |
1 | 2019-07-25 08:34:35 | announced | |
⏵ 2 | 2019-08-22 01:44:53 | announced | Updated publication reference for PubMed record(s): 31417895. |
Publication List
Nunes J, Charneira C, Nunes C, Gouveia-Fernandes S, Serpa J, Morello J, Antunes AMM, A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications. Front Chem, 7():532(2019) [pubmed] |
Keyword List
submitter keyword: Glycidamide, histones, mass spectrometry, adductomics |
Contact List
Alexandra MM Antunes |
contact affiliation | Centro de Química Estrutural, Instituto Superior Técnico, ULisboa, Lisboa, Portugal |
contact email | alexandra.antunes@tecnico.ulisboa.pt |
lab head | |
Judit Morello |
contact affiliation | CQE, IST |
contact email | judit.morello@tecnico.ulisboa.pt |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD013683
- Label: PRIDE project
- Name: Identification of histone adducts with glycidamide