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PXD013528

PXD013528 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFFPE proteomes for Group 3 and Group 4 subtypes of paediatric medulloblastoma
DescriptionThese data were generated in May of 2016 on a Thermo Q-Exactive at the University of Cape Town in South Africa. Samples were drawn from 48 cases of malignant medulloblastoma that were added to the FFPE archive between 1988 and 2014 under approval from the University of Cape Town Faculty of Health Sciences Human Research Ethics Committee (HREC 149/2014). Assignment to Group 3 or Group 4 categories was performed via Nanostring analysis and IHC (other subtypes were also analyzed in the larger study). Five distinct samples from each of the two Groups were subjected to LC-MS/MS. After conversion to mzML, a total of 245,589 tandem mass spectra were available, of which 36% corresponded to doubly-charged precursor ions. Over all ten experiments, tandem mass spectra were acquired at a rate of 4.55 Hz. MS/MS scans averaged a peak density average of 148 peaks per spectrum. More complete information is available in Omesan Nair's Ph.D. Dissertation: http://hdl.handle.net/11427/26896.
HostingRepositoryMassIVE
AnnounceDate2019-04-16
AnnouncementXMLSubmission_2019-04-16_08:02:33.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterDavid L. Tabb
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListCarbamidomethyl; Methyl; Dimethyl; Oxidation; Dioxidation
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-04-16 07:43:28ID requested
12019-04-16 08:02:34announced
Publication List
no publication
Keyword List
submitter keyword: FFPE, medulloblastoma, brain
Contact List
Jonathan M Blackburn
contact affiliationDivision of Computational and Systems Biology, Department of Integrative Biomedical Science, Faculty of Health Science, University of Cape Town, South Africa.
contact emailjonathan.blackburn@uct.ac.za
lab head
David L. Tabb
contact affiliationStellenbosch University
contact emaildtabb@sun.ac.za
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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