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PXD013425

PXD013425 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman serum interactome of snake-derived antimicrobial peptide Ctn[15-34]
DescriptionThe affinity purification/MS identification methodology reported here can be viewed as a routine pharmacoproteomic approach to investigate the serum interactome of peptide drugs, identifying proteins affecting bioavailability and thus assisting the peptide drug development process. The specific results described here enlighten the serum stability issues of peptide Ctn[15-34] and ratifiy its promising future as an anti-infective lead.
HostingRepositoryPRIDE
AnnounceDate2019-05-06
AnnouncementXMLSubmission_2019-05-14_07:26:51.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterClara Pérez-Peinado
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-04-09 07:17:21ID requested
12019-05-06 06:26:33announced
22019-05-14 07:26:53announcedUpdated publication reference for PubMed record(s): 31051282.
Publication List
P, é, rez-Peinado C, Defaus S, Sans-Comerma L, Valle J, Andreu D, Decoding the human serum interactome of snake-derived antimicrobial peptide Ctn[15-34]: Toward an explanation for unusually long half-life. J Proteomics, 204():103372(2019) [pubmed]
Keyword List
submitter keyword: Human serum, antimicrobial peptide, LC-MS/MS, peptide proteolytic resistance
Contact List
David Andreu
contact affiliationDepartament of Experimental and Health Sciences, Pompeu Fabra University, Barcelona, Spain
contact emaildavid.andreu@upf.edu
lab head
Clara Pérez-Peinado
contact affiliationPompeu Fabra University
contact emailclara.perez@upf.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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