PXD013319

PXD013319 is an original dataset announced via ProteomeXchange.

Title	Thermal proteome profiling of darobactin in Escherichia coli
Description	We performed two dimensional thermal proteome profiling (2D-TPP) of darobactin to study its impact in Escherichia coli.
HostingRepository	PRIDE
AnnounceDate	2019-10-29
AnnouncementXML	Submission_2020-01-02_06:32:31.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andre Mateus
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-04-01 01:01:42	ID requested
1	2019-10-29 04:37:43	announced
⏵ 2	2020-01-02 06:32:32	announced	2020-01-02: Updated publication reference for PubMed record(s): 31747680.

Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, B, ö, hringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O'Rourke A, Nelson KE, Hiller S, Noinaj N, Sch, ä, berle TF, D'Onofrio A, Lewis K, A new antibiotic selectively kills Gram-negative pathogens. Nature, 576(7787):459-464(2019) [pubmed]

curator keyword: Biological

submitter keyword: thermal proteome profiling, Escherichia coli, darobactin, drugs, target engagement

Mikhail M. Savitski
contact affiliation	European Molecular Biology Laboratory
contact email	mikhail.savitski@embl.de
lab head
Andre Mateus
contact affiliation	European Molecular Biology Laboratory
contact email	andre.mateus@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD013319

PRIDE project URI

• PRIDE
  1. PXD013319
     1. Label: PRIDE project
     2. Name: Thermal proteome profiling of darobactin in Escherichia coli