PXD013271 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Multilayered control of protein turnover by TORC1 and ATG1 |
Description | To study TORC1-Atg1 signaling comprehensively and to identify potential additional foci of crosstalk, we chose a mass spectrometry (MS)-based phosphoproteomics strategy combing global proteomics screens in vivo with targeted analyses using in vitro kinase reactions. We present the currently largest compendium of rapamycin-sensitive phosphorylation events in the yeast Saccharomyces cerevisiae, identify numerous unknown TORC1 and Atg1 downstream phosphorylation events, and characterize hitherto unknown, functionally relevant TORC1 target sites on defined Atg proteins. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:04:16.685.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Joern Dengjel |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | phosphorylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-03-27 08:12:16 | ID requested | |
1 | 2019-09-30 07:56:28 | announced | |
⏵ 2 | 2024-10-22 04:04:24 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1016/j.celrep.2019.08.069; |
Hu Z, Raucci S, Jaquenoud M, Hatakeyama R, Stumpe M, Rohr R, Reggiori F, De Virgilio C, Dengjel J, Multilayered Control of Protein Turnover by TORC1 and Atg1. Cell Rep, 28(13):3486-3496.e6(2019) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: autophagy,Yeast, Saccharomyces cerevisiae, phosphorylation, TORC1, phosphoproteomics, rapamycin |
Contact List
Joern Dengjel |
contact affiliation | Dr. Jörn Dengjel Prof. for Biochemistry and Cell Biology Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 |
contact email | joern.dengjel@unifr.ch |
lab head | |
Joern Dengjel |
contact affiliation | University of Fribourg |
contact email | joern.dengjel@medizin.uni-freiburg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD013271
- Label: PRIDE project
- Name: Multilayered control of protein turnover by TORC1 and ATG1