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PXD013271

PXD013271 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMultilayered control of protein turnover by TORC1 and ATG1
DescriptionTo study TORC1-Atg1 signaling comprehensively and to identify potential additional foci of crosstalk, we chose a mass spectrometry (MS)-based phosphoproteomics strategy combing global proteomics screens in vivo with targeted analyses using in vitro kinase reactions. We present the currently largest compendium of rapamycin-sensitive phosphorylation events in the yeast Saccharomyces cerevisiae, identify numerous unknown TORC1 and Atg1 downstream phosphorylation events, and characterize hitherto unknown, functionally relevant TORC1 target sites on defined Atg proteins.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:04:16.685.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJoern Dengjel
SpeciesList scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationListphosphorylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-03-27 08:12:16ID requested
12019-09-30 07:56:28announced
22024-10-22 04:04:24announced2024-10-22: Updated project metadata.
Publication List
10.1016/j.celrep.2019.08.069;
Hu Z, Raucci S, Jaquenoud M, Hatakeyama R, Stumpe M, Rohr R, Reggiori F, De Virgilio C, Dengjel J, Multilayered Control of Protein Turnover by TORC1 and Atg1. Cell Rep, 28(13):3486-3496.e6(2019) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: autophagy,Yeast, Saccharomyces cerevisiae, phosphorylation, TORC1, phosphoproteomics, rapamycin
Contact List
Joern Dengjel
contact affiliationDr. Jörn Dengjel Prof. for Biochemistry and Cell Biology Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631
contact emailjoern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliationUniversity of Fribourg
contact emailjoern.dengjel@medizin.uni-freiburg.de
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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