PXD013271

PXD013271 is an original dataset announced via ProteomeXchange.

Title	Multilayered control of protein turnover by TORC1 and ATG1
Description	To study TORC1-Atg1 signaling comprehensively and to identify potential additional foci of crosstalk, we chose a mass spectrometry (MS)-based phosphoproteomics strategy combing global proteomics screens in vivo with targeted analyses using in vitro kinase reactions. We present the currently largest compendium of rapamycin-sensitive phosphorylation events in the yeast Saccharomyces cerevisiae, identify numerous unknown TORC1 and Atg1 downstream phosphorylation events, and characterize hitherto unknown, functionally relevant TORC1 target sites on defined Atg proteins.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:04:16.685.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joern Dengjel
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-03-27 08:12:16	ID requested
1	2019-09-30 07:56:28	announced
⏵ 2	2024-10-22 04:04:24	announced	2024-10-22: Updated project metadata.

10.1016/j.celrep.2019.08.069;

Hu Z, Raucci S, Jaquenoud M, Hatakeyama R, Stumpe M, Rohr R, Reggiori F, De Virgilio C, Dengjel J, Multilayered Control of Protein Turnover by TORC1 and Atg1. Cell Rep, 28(13):3486-3496.e6(2019) [pubmed]

curator keyword: Biological

submitter keyword: autophagy,Yeast, Saccharomyces cerevisiae, phosphorylation, TORC1, phosphoproteomics, rapamycin

Joern Dengjel
contact affiliation	Dr. Jörn Dengjel Prof. for Biochemistry and Cell Biology Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631
contact email	joern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliation	University of Fribourg
contact email	joern.dengjel@medizin.uni-freiburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/09/PXD013271

PRIDE project URI

• PRIDE
  1. PXD013271
     1. Label: PRIDE project
     2. Name: Multilayered control of protein turnover by TORC1 and ATG1