PXD013106

PXD013106 is an original dataset announced via ProteomeXchange.

Title	MonoMac6 (MM6) cells proteomics LC-MS/MS
Description	MicroRNAs (miRs) are small non-coding RNAs, which control the expression of target genes by either translational repression or RNA degradation, known as canonical miR function. MiR-328 has a non-canonical function and can activate gene expression by antagonizing the activity of heterogeneous ribonuclear protein E2 (hnRNP E2). The global importance of such non-canonical miR function is not yet known. In order to achieve a better understanding of the non-canonical miR activity, a compartment specific tandem mass tag (TMT)-based proteomic analysis in differentiated MonoMac6 (MM6) cells was performed.
HostingRepository	PRIDE
AnnounceDate	2019-11-27
AnnouncementXML	Submission_2019-11-27_02:23:11.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Elena Ossipova
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-03-15 08:49:00	ID requested
⏵ 1	2019-11-27 02:23:13	announced

Saul MJ, Hegewald AB, Emmerich AC, Ossipova E, Vogel M, Baumann I, Kultima K, Lengqivst J, Steinhilber D, Jakobsson PJ, Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes. Front Pharmacol, 10():640(2019) [pubmed]

submitter keyword: MonoMac6 (MM6) cells, inflammation

Per-Johan Jakobsson
contact affiliation	Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital in Solna, Stockholm, Sweden
contact email	Per-Johan.Jakobsson@ki.se
lab head
Elena Ossipova
contact affiliation	Karolinska Institute
contact email	Elena.Ossipova@ki.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/11/PXD013106

PRIDE project URI

• PRIDE
  1. PXD013106
     1. Label: PRIDE project
     2. Name: MonoMac6 (MM6) cells proteomics LC-MS/MS