PXD013032

PXD013032 is an original dataset announced via ProteomeXchange.

Title	Identification of Siglec-E-ligand candidates on BCL-1 mouse B cell line by proximity labeling
Description	Siglec-E is a member of Siglec family of glycan recognition proteins involved in the regulation of myeloid cell activities. Siglec-E preferentially recognizes disialic acid, a glycan epitope consisting of two sialic acids conjugated in alpha2-8 linkage (Zhang JQ et al., Eur J Immunol. 2004, 34:1175-84). BCL-1, a mouse B cell line, expresses disialic acid epitope (Wang SH et al., Glycobiology. 2013, 23:677-89). In this experiment, we attempted at identifying the ligands of Siglec-E on BCL-1 by applying the proximity labeling method we developed (Chang L et al., J Proteome Res. 2017, 16:3929-41).
HostingRepository	PRIDE
AnnounceDate	2022-02-25
AnnouncementXML	Submission_2022-02-24_17:24:33.890.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yi-Ju Chen
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-03-11 02:18:07	ID requested
⏵ 1	2022-02-24 17:24:34	announced

Chang L, Chen YJ, Fan CY, Tang CJ, Chen YH, Low PY, Ventura A, Lin CC, Chen YJ, Angata T, Identification of Siglec Ligands Using a Proximity Labeling Method. J Proteome Res, 16(10):3929-3941(2017) [pubmed]

curator keyword: Biological

submitter keyword: Mouse, B cell, Siglec-E, sialic acid, ligand, LC-MSMS

Yi-Ju Chen
contact affiliation	Institute of Chemistry, Academia Sinica
contact email	tp7249@gmail.com
lab head
Yi-Ju Chen
contact affiliation	Academia Sinica
contact email	tp7249@gmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD013032
     1. Label: PRIDE project
     2. Name: Identification of Siglec-E-ligand candidates on BCL-1 mouse B cell line by proximity labeling