PXD012739

PXD012739 is an original dataset announced via ProteomeXchange.

Title	Contribution of ShkA dysregulation to the cdG0 phenotype
Description	The ShkA-ShpA-TacA phosphorelay regulates stalk biogenesis and G1-S phase transition in Caulobacter crescentus. Histidine kinase activity of ShkA is c-di-GMP dependent and a strain lacking c-di-GMP (cdG0) shows a number of phenotypic aberrations. In this project, we aim at disentangling the contribution of ShkA-ShpA-TacA pathway dysregulation to the cdG0 phenotype by profiling the proteomes of mutants that constitutively activate or deactivate TacA target gene expression.
HostingRepository	PRIDE
AnnounceDate	2019-12-16
AnnouncementXML	Submission_2020-02-17_21:07:40.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD012739
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Alexander Schmidt
SpeciesList	scientific name: Caulobacter sp. 736; NCBI TaxID: 2172651;
ModificationList	Oxidation; Acetyl; Carbamidomethyl
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2019-02-18 00:21:20	ID requested
1	2019-12-16 08:21:31	announced
⏵ 2	2020-02-17 21:07:41	announced	2020-02-18: Updated publication reference for PubMed record(s): 32041947.

Kaczmarczyk A, Hempel AM, von Arx C, B, ö, hm R, Dubey BN, Nesper J, Schirmer T, Hiller S, Jenal U, Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter. Nat Commun, 11(1):816(2020) [pubmed]

submitter keyword: C. cresentus, ESI, LFQ, Oribtrap, ShkA

Alexander Schmidt
contact affiliation	Biozentrum, University of Basel, 4056 Basel, Switzerland
contact email	alex.schmidt@unibas.ch
lab head
Alexander Schmidt
contact affiliation	Proteomics Core Facility
contact email	alex.schmidt@unibas.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/12/PXD012739

PRIDE project URI

• PRIDE
  1. PXD012739
     1. Label: PRIDE project
     2. Name: Contribution of ShkA dysregulation to the cdG0 phenotype