PXD012691

PXD012691 is an original dataset announced via ProteomeXchange.

Title	Arsenic induces reversible nitrosative stress and behavioural changes in mice
Description	Studies on exposure of mice to Arsenic, combined with unique tools developed in our laboratory to determine the consequences of NO formation in mouse brain and neuronal cell culture, will probe mechanistic pathways of nitrosative damage operable in behavioural development.
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_08:56:21.800.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Haitham Amal
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	carbamoylated residue
Instrument	orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2019-02-13 04:00:57	ID requested
⏵ 1	2021-09-08 08:56:22	announced

Amal H, Gong G, Yang H, Joughin BA, Wang X, Knutson CG, Kartawy M, Khaliulin I, Wishnok JS, Tannenbaum SR, Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide. Int J Mol Sci, 21(11):(2020) [pubmed]

submitter keyword: arsenic, nitric oxide, brain, autism. s-nitrosylation, snotrap

Steven Tannenbaum
contact affiliation	Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139
contact email	srt@mit.edu
lab head
Haitham Amal
contact affiliation	Massachusetts Institute of Technology (MIT)
contact email	hamal@mit.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD012691

PRIDE project URI

• PRIDE
  1. PXD012691
     1. Label: PRIDE project
     2. Name: Arsenic induces reversible nitrosative stress and behavioural changes in mice