PXD012636

PXD012636 is an original dataset announced via ProteomeXchange.

Title	The protein expression landscape of the heart across humans and model organisms
Description	Here we perform a global analysis of cardiac protein expression in humans and model organisms across cardiac chambers using quantitative mass spectrometry based proteomics. We measure >6,500 proteins in each species and create a global comparison of cardiac protein expression across species. The data was collected in an online database for access by cardiac researchers. This data will enable researchers to e. g. choose the best model organism for a scientific question at hand, facilitate transfer of knowledge between studies conducted in different model organisms and help to integrate knowledge of cardiac physiology and disease to point to new leads in cardiac research.
HostingRepository	PRIDE
AnnounceDate	2023-09-13
AnnouncementXML	Submission_2023-09-13_03:42:10.617.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	UlrikeLeurs
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Equus caballus (Horse); NCBI TaxID: 9796; scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-02-08 02:35:14	ID requested
1	2021-02-03 00:29:02	announced
⏵ 2	2023-09-13 03:42:11	announced	2023-09-13: Updated project metadata.

Linscheid N, Santos A, Poulsen PC, Mills RW, Calloe K, Leurs U, Ye JZ, Stolte C, Thomsen MB, Bentzen BH, Lundegaard PR, Olesen MS, Jensen LJ, Olsen JV, Lundby A, Quantitative proteome comparison of human hearts with those of model organisms. PLoS Biol, 19(4):e3001144(2021) [pubmed]

submitter keyword: LC-MS, proteomics, species, heart, proteomes, cardiac proteomics

AliciaLundby
contact affiliation	Department of Biomedical Sciences, Affiliated with The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen.
contact email	alicia.lundby@sund.ku.dk
lab head
UlrikeLeurs
contact affiliation	University of Copenhagen
contact email	ulrike.leurs@sund.ku.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD012636

PRIDE project URI

• PRIDE
  1. PXD012636
     1. Label: PRIDE project
     2. Name: The protein expression landscape of the heart across humans and model organisms