PXD012630 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Estrogen Receptor alpha (ERα) interactome before and after RNAse treatment in human breast cancer cells nuclei |
Description | The Estrogen Receptor alpha (ERα), is a member of the nuclear receptor superfamily of trancriptional regulators that mediates estrogen signaling in hormone-responsive tumors controlling key cellular functions by assembling in large functional multiprotein complexes. Interaction proteomics coupled to mass spectrometry (MS) was applied to deeply characterize the nuclear interactors partners whom association with the receptor is mediated by RNAs |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:52:58.818.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Tuula Nyman |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-02-08 02:32:26 | ID requested | |
1 | 2019-07-29 06:23:25 | announced | |
2 | 2019-09-25 01:57:27 | announced | 2019-09-25: Updated publication reference for PubMed record(s): 31527615. |
⏵ 3 | 2024-10-22 04:53:07 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1038/s41597-019-0179-2; |
Nassa G, Giurato G, Salvati A, Gigantino V, Pecoraro G, Lamberti J, Rizzo F, Nyman TA, Tarallo R, Weisz A, interactome of hormone-dependent human breast cancer cell nuclei. Sci Data, 6(1):173(2019) [pubmed] |
Keyword List
submitter keyword: breast cancer, RNAse treatment,estrogen receptor alpha, interactome |
Contact List
Tuula Nyman |
contact affiliation | Head of Proteomics |
contact email | tuula.nyman@medisin.uio.no |
lab head | |
Tuula Nyman |
contact affiliation | University of Oslo |
contact email | tuula.nyman@medisin.uio.no |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/07/PXD012630 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD012630
- Label: PRIDE project
- Name: Estrogen Receptor alpha (ERα) interactome before and after RNAse treatment in human breast cancer cells nuclei