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PXD012602

PXD012602 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleConodipine phospholipase
DescriptionUsing proteomics methods, we determined the full sequences of three conodipines (Cdpi-P1, -P2 and -P3). Conodipine-P1-3 have conserved consensus catalytic domain residues, including the Asp/His dyad. The activities of the native Conodipine-Ps were evaluated by conventional colorimetric and by MS-based methods, which provide the first detailed cone snail venom conodipine activity monitored by mass spectrometry. Conodipines can have medicinal applications such inhibition of cancer proliferation, bacterial and viral infections among others.
HostingRepositoryMassIVE
AnnounceDate2019-03-08
AnnouncementXMLSubmission_2019-03-08_04:35:03.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterClay Davis
SpeciesList scientific name: Conus purpurascens; NCBI TaxID: 41690;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-02-06 09:00:02ID requested
12019-03-08 04:35:04announced
Publication List
no publication
Keyword List
submitter keyword: conodipines, phospholipase, cone snails, venom, venomics, proteomics
Contact List
Frank Mari
contact affiliationNational Institute of Standards and Technology
contact emailfrank.mari@nist.gov
lab head
Clay Davis
contact affiliationNational Institute of Standards and Technology
contact emailclay.davis@nist.gov
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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