PXD012587

PXD012587 is an original dataset announced via ProteomeXchange.

Title	Human enamel peptides LC-MS/MS
Description	Recently, enamel peptides revealed their critical role in sex classification of old skeletal remains. In particular, the presence of protein AMELY (amelogenin isoform Y) within the enamel dental tissue is restricted to the male sex only, while AMELX (isoform X) can be found in both sexes. AMELY can be easily detected through peptide SM(ox)IRPPY by means of LC-MS/MS and retrieved from ion chromatograms (exact mass [M+2H]+2 440.2233 m/z). In this paper, we exploited the dimorphic features of the amelogenin protein to unravel the sex of the so-called ‘Lovers of Modena’, two Late Antique individuals whose skeletons were intentionally buried hand-in-hand.
HostingRepository	PRIDE
AnnounceDate	2019-10-31
AnnouncementXML	Submission_2019-10-31_05:00:26.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Federico Lugli
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	dehydrated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-02-01 04:02:46	ID requested
⏵ 1	2019-10-31 05:00:27	announced

Lugli F, Di Rocco G, Vazzana A, Genovese F, Pinetti D, Cilli E, Carile MC, Silvestrini S, Gabanini G, Arrighi S, Buti L, Bortolini E, Cipriani A, Figus C, Marciani G, Oxilia G, Romandini M, Sorrentino R, Sola M, Benazzi S, Enamel peptides reveal the sex of the Late Antique 'Lovers of Modena'. Sci Rep, 9(1):13130(2019) [pubmed]

curator keyword: Biological

submitter keyword: Human, enamel, peptides, sex, archaeology

Giulia Di Rocco
contact affiliation	Department of Life Sciences, University of Modena and Reggio Emilia
contact email	giulia.dirocco@unimore.it
lab head
Federico Lugli
contact affiliation	Department of Cultural Heritage - University of Bologna
contact email	federico.lugli6@unibo.it
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD012587

PRIDE project URI

• PRIDE
  1. PXD012587
     1. Label: PRIDE project
     2. Name: Human enamel peptide LC-MS/MS