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PXD012535

PXD012535 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleUSP7: combing tools towards selectivity
DescriptionActive-site probes based on the ubiquitin scaffold have been successfully applied as tools to determine the levels of active deubiquitinating enzymes (DUBs). Here, we show the development of a Ub-based reagent selective for the DUB USP7. This concept can be applied for the generation of other new selective reagents.
HostingRepositoryPRIDE
AnnounceDate2019-03-13
AnnouncementXMLSubmission_2019-05-14_07:17:13.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRomán González-Prieto
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-01-28 06:48:33ID requested
12019-03-13 12:36:49announced
22019-05-14 07:17:15announcedUpdated publication reference for PubMed record(s): 30972393.
Publication List
Gjonaj L, Sapmaz A, Gonz, á, lez-Prieto R, Vertegaal ACO, Flierman D, Ovaa H, USP7: combining tools towards selectivity. Chem Commun (Camb), 55(35):5075-5078(2019) [pubmed]
Keyword List
curator keyword: Technical
submitter keyword: Ubiquitin, DUBs, USP7
Contact List
Alfred C.O. Vertegaal
contact affiliationDepartment of Cell and Chemical Biology, Leiden University Medical Center (LUMC), Einthovenweg 20, 2333, ZC, Leiden, The Netherlands.
contact emailvertegaal@lumc.nl
lab head
Román González-Prieto
contact affiliationLeiden University Medical Center (LUMC)
contact emailR.Gonzalez_Prieto@lumc.nl
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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