PXD012465

PXD012465 is an original dataset announced via ProteomeXchange.

Title	Analysis of human fetuin peptides originating from the serum of individuals, part 2
Description	Human fetuin, also known as α-2-HS glycoprotein, is an abundant glycoprotein circulating in human plasma. AHSG is the gene symbol responsible for coding the fetuin protein. A frequent polymorphism of AHSG results in two alleles, AHSG*1 and AHSG*2, which producing three genotypes (AHSG*1, AHSG*2, and heterozygous AHSG1/2). The backbone amino acid sequences of fetuin coded by AHSG*1 and AHSG*2 genes differ from each other in two amino acids including one O-glycosylation site (position 256). We aim to describe human’s individual fetuin proteoform profiles directly isolated from serum of healthy and septic people, focusing on potential glycoproteogenomics correlations, e.g. how gene polymorphisms may affect glycosylation.
HostingRepository	PRIDE
AnnounceDate	2019-05-20
AnnouncementXML	Submission_2019-05-20_01:44:46.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD012465
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	yuhsien lin
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Phospho; Oxidation; Carbamidomethyl
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2019-01-22 03:15:19	ID requested
⏵ 1	2019-05-20 01:44:47	announced

Dataset with its publication pending

curator keyword: Biological

submitter keyword: Human, fetuin, glycopeptides, N-glycosylation, O-glycosylation, phosphorylation, gene polymorphism

Albert J R Heck
contact affiliation	Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Science4Life, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands
contact email	A.J.R.Heck@uu.nl
lab head
yuhsien lin
contact affiliation	Utrecht University
contact email	y.lin1@uu.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/05/PXD012465

PRIDE project URI

• PRIDE
  1. PXD012465
     1. Label: PRIDE project
     2. Name: Analysis of human fetuin peptides originating from the serum of individuals, part 2