PXD012430 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mouse brain LC-MS - KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a |
Description | To investigate the molecular mechanisms by which KIBRA regulates exosome secretion, we performed mass spectral (MS) analysis and an isobaric tag for relative and absolute quantitation (iTRAQ) assay to screen the differentially-expressed proteins in the brains of KIBRA-KO mice compared with their WT littermates. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:52:27.822.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Lin Song |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | iTRAQ8plex-116 reporter+balance reagent acylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-01-18 07:41:45 | ID requested | |
1 | 2019-04-02 08:40:58 | announced | |
2 | 2019-05-14 07:20:03 | announced | Updated publication reference for PubMed record(s): 30967557. |
⏵ 3 | 2024-10-22 04:52:35 | announced | 2024-10-22: Updated project metadata. |
Publication List
Song L, Tang S, Han X, Jiang Z, Dong L, Liu C, Liang X, Dong J, Qiu C, Wang Y, Du Y, KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a. Nat Commun, 10(1):1639(2019) [pubmed] |
10.1038/s41467-019-09720-x; |
Keyword List
curator keyword: Biological |
submitter keyword: KIBRA, Brain, LC-MS, Mouse |
Contact List
Yifeng Du |
contact affiliation | Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, No. 324 Jingwuweiqi Road, Jinan, 250021, Shandong, P. R. China. |
contact email | du-yifeng@hotmail.com |
lab head | |
Lin Song |
contact affiliation | Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, Jinan, Shandong, P. R. China. |
contact email | zzusonglin@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/04/PXD012430 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD012430
- Label: PRIDE project
- Name: Mouse brain LC-MS - KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a