PXD012430

PXD012430 is an original dataset announced via ProteomeXchange.

Title	Mouse brain LC-MS - KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a
Description	To investigate the molecular mechanisms by which KIBRA regulates exosome secretion, we performed mass spectral (MS) analysis and an isobaric tag for relative and absolute quantitation (iTRAQ) assay to screen the differentially-expressed proteins in the brains of KIBRA-KO mice compared with their WT littermates.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:52:27.822.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lin Song
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-01-18 07:41:45	ID requested
1	2019-04-02 08:40:58	announced
2	2019-05-14 07:20:03	announced	Updated publication reference for PubMed record(s): 30967557.
⏵ 3	2024-10-22 04:52:35	announced	2024-10-22: Updated project metadata.

Song L, Tang S, Han X, Jiang Z, Dong L, Liu C, Liang X, Dong J, Qiu C, Wang Y, Du Y, KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a. Nat Commun, 10(1):1639(2019) [pubmed]

10.1038/s41467-019-09720-x;

curator keyword: Biological

submitter keyword: KIBRA, Brain, LC-MS, Mouse

Yifeng Du
contact affiliation	Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, No. 324 Jingwuweiqi Road, Jinan, 250021, Shandong, P. R. China.
contact email	du-yifeng@hotmail.com
lab head
Lin Song
contact affiliation	Department of Neurology, Shandong Provincial Hospital affiliated to Shandong University, Jinan, Shandong, P. R. China.
contact email	zzusonglin@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/04/PXD012430

PRIDE project URI

• PRIDE
  1. PXD012430
     1. Label: PRIDE project
     2. Name: Mouse brain LC-MS - KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a