PXD012369

PXD012369 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Inhibition of T cell activation and function by the CIN85 adaptor protein
Description	CIN85 is ubiquitously expressed adaptor protein. In T cells, CIN85 is recruited to the TCR signaling complex and inhibit TCR signaling. To reveal the molecular function of CIN85-mediated inhibition, we performed Flag-CIN85 (CIN85dA) immuno-precipitation and identified the binding proteins. As a negative control, we used deletion mutant of CIN85 (CIN85PR).
HostingRepository	jPOST
AnnounceDate	2019-01-16
AnnouncementXML	Submission_2022-09-18_04:04:52.292.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yusuke Kawashima
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-01-15 22:37:28	ID requested
1	2019-01-15 22:37:32	announced
2	2020-08-21 17:36:02	announced	2020-08-22: Updated PubMed.
3	2021-02-04 17:12:17	announced	2021-02-04: Updated FTP location.
⏵ 4	2022-09-18 04:04:53	announced	2022-09-18: Updated FTP location.

Publication List

Kong MS, Hashimoto-Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, Onishi R, Carpino N, Ohara O, Kurosaki T, Phua KK, Saito T, Inhibition of T cell activation and function by the adaptor protein CIN85. Sci Signal, 12(567):(2019) [pubmed]

Kong MS, Hashimoto-Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, Onishi R, Carpino N, Ohara O, Kurosaki T, Phua KK, Saito T, Inhibition of T cell activation and function by the adaptor protein CIN85. Sci Signal, 12(567):(2019) [pubmed]

Keyword List

submitter keyword: CIN85, TCR, adaptor

submitter keyword: CIN85, TCR, adaptor

Contact List

Takashi Saito
lab head
Yusuke Kawashima
contact affiliation	Kazusa DNA Research Institute
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000545/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000545/