PXD012341
PXD012341 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Improving Mass Spectrometry Analysis of Protein Structures with Arginine-Selective Chemical Cross-linkers |
Description | we develop a series of arginine selective bifunctional aromatic glyoxal cross-linkers (ArGOs) and demonstrate their ability to cross-link model proteins and a protein complex. We also introduce the first arginine-lysine heterobifunctional cross-linker (KArGO), which provides significantly greater surface coverage than the corresponding homobifunctional reagents (e.g. ArGOs and BS3), due to access to the combined abundances of lysine and arginine residues. |
HostingRepository | iProX |
AnnounceDate | 2019-01-14 |
AnnouncementXML | Submission_2019-12-10_22:30:48.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yong Cao |
SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2019-01-14 23:42:24 | ID requested | |
1 | 2019-01-14 23:43:41 | announced | |
⏵ 2 | 2019-12-10 22:30:49 | announced | 2019-12-11: Update publication information. |
Publication List
Jones AX, Cao Y, Tang YL, Wang JH, Ding YH, Tan H, Chen ZL, Fang RQ, Yin J, Chen RC, Zhu X, She Y, Huang N, Shao F, Ye K, Sun RX, He SM, Lei X, Dong MQ, Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers. Nat Commun, 10(1):3911(2019) [pubmed] |
Keyword List
submitter keyword: LC-MS/MS, CXMS, Arginine-Selective Cross-linkers |
Contact List
Meng-Qiu Dong | |
---|---|
contact affiliation | National Institute of Biological Sciences, Beijing |
contact email | dongmengqiu@nibs.ac.cn |
lab head | |
Yong Cao | |
contact affiliation | National Institute of Biological Sciences, Beijing |
contact email | caoyong@nibs.ac.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |