PXD012341

PXD012341 is an original dataset announced via ProteomeXchange.

Title	Improving Mass Spectrometry Analysis of Protein Structures with Arginine-Selective Chemical Cross-linkers
Description	we develop a series of arginine selective bifunctional aromatic glyoxal cross-linkers (ArGOs) and demonstrate their ability to cross-link model proteins and a protein complex. We also introduce the first arginine-lysine heterobifunctional cross-linker (KArGO), which provides significantly greater surface coverage than the corresponding homobifunctional reagents (e.g. ArGOs and BS3), due to access to the combined abundances of lysine and arginine residues.
HostingRepository	iProX
AnnounceDate	2019-01-14
AnnouncementXML	Submission_2019-12-10_22:30:48.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yong Cao
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-01-14 23:42:24	ID requested
1	2019-01-14 23:43:41	announced
⏵ 2	2019-12-10 22:30:49	announced	2019-12-11: Update publication information.

Jones AX, Cao Y, Tang YL, Wang JH, Ding YH, Tan H, Chen ZL, Fang RQ, Yin J, Chen RC, Zhu X, She Y, Huang N, Shao F, Ye K, Sun RX, He SM, Lei X, Dong MQ, Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers. Nat Commun, 10(1):3911(2019) [pubmed]

submitter keyword: LC-MS/MS, CXMS, Arginine-Selective Cross-linkers

Meng-Qiu Dong
contact affiliation	National Institute of Biological Sciences, Beijing
contact email	dongmengqiu@nibs.ac.cn
lab head
Yong Cao
contact affiliation	National Institute of Biological Sciences, Beijing
contact email	caoyong@nibs.ac.cn
dataset submitter

iProX dataset URI