PXD012332

PXD012332 is an original dataset announced via ProteomeXchange.

Title	Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production
Description	Our study is the first investigation of proteome of oleaginous yeast Rhotodorula toruloides during conversion of xylose into lipids. We performed comparative proteomics of R. toruloides during cultivation of two carbon sources: glucose and xylose. Proteome analysis revealed significantly lower levels of ribosomal proteins and translation associated factors in xylose-grown cells as compared to glucose-grown cells. We showed that proteins involved in sugar transport, phospholipid and leucine biosynthesis as well as peroxisomal beta-oxidation and oxidative stress response were differentially regulated in response to carbon source.
HostingRepository	PRIDE
AnnounceDate	2019-08-08
AnnouncementXML	Submission_2019-08-08_07:47:16.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ievgeniia Tiukova
SpeciesList	scientific name: Rhodotorula toruloides; NCBI TaxID: 5286;
ModificationList	2-pyrrolidone-5-carboxylic acid (Gln); deaminated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-01-14 07:28:17	ID requested
⏵ 1	2019-08-08 07:47:18	announced

Tiukova IA, Brandenburg J, Blomqvist J, Sampels S, Mikkelsen N, Skaugen M, Arntzen M Ø, Nielsen J, Sandgren M, Kerkhoven EJ, during lipid production. Biotechnol Biofuels, 12():137(2019) [pubmed]

curator keyword: Biological

submitter keyword: Rhodotorula toruloides, proteome, xylose, lipid production

Jens Nielsen
contact affiliation	Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, SE-412 96 Göteborg, Sweden
contact email	nielsenj@chalmers.se
lab head
Ievgeniia Tiukova
contact affiliation	Chalmers University of Technology
contact email	tiukova.ievgeniia@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD012332

PRIDE project URI

• PRIDE
  1. PXD012332
     1. Label: PRIDE project
     2. Name: Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production