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PXD012316

PXD012316 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphoproteomics of endothelin signalling
DescriptionTime resolved phosphorylation changes were measured the melanoma cell lines A2058 and UACC257. An endothelin B receptor knockout of UACC257 was processed in parallel. Protein abundance was also compared at the latest time point of the study (90 min) using DIA-SWATH
HostingRepositoryPRIDE
AnnounceDate2019-10-11
AnnouncementXMLSubmission_2019-10-11_08:00:44.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlexander Schäfer
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList6x(13)C,4x(15)N labeled L-arginine; 6x(13)C,2x(15)N labeled L-lysine; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Elite; TripleTOF 6600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-01-14 00:52:25ID requested
12019-07-08 02:48:56announced
22019-10-11 08:00:46announced2019-10-11: Updated project metadata.
Publication List
Sch, ä, fer A, Gjerga E, Welford RW, Renz I, Lehembre F, Groenen PM, Saez-Rodriguez J, Aebersold R, Gstaiger M, Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data. Mol Syst Biol, 15(8):e8828(2019) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: endothelin, phosphoproteomics, signalling
Contact List
Ruedi Aebersold
contact affiliationDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zurich, Switzerland
contact emailaebersold@imsb.biol.ethz.ch
lab head
Alexander Schäfer
contact affiliationETH Zurich
contact emailschaefer@imsb.biol.ethz.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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