PXD012316 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Phosphoproteomics of endothelin signalling |
Description | Time resolved phosphorylation changes were measured the melanoma cell lines A2058 and UACC257. An endothelin B receptor knockout of UACC257 was processed in parallel. Protein abundance was also compared at the latest time point of the study (90 min) using DIA-SWATH |
HostingRepository | PRIDE |
AnnounceDate | 2019-10-11 |
AnnouncementXML | Submission_2019-10-11_08:00:44.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Alexander Schäfer |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | 6x(13)C,4x(15)N labeled L-arginine; 6x(13)C,2x(15)N labeled L-lysine; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Elite; TripleTOF 6600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-01-14 00:52:25 | ID requested | |
1 | 2019-07-08 02:48:56 | announced | |
⏵ 2 | 2019-10-11 08:00:46 | announced | 2019-10-11: Updated project metadata. |
Publication List
Sch, ä, fer A, Gjerga E, Welford RW, Renz I, Lehembre F, Groenen PM, Saez-Rodriguez J, Aebersold R, Gstaiger M, Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data. Mol Syst Biol, 15(8):e8828(2019) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: endothelin, phosphoproteomics, signalling |
Contact List
Ruedi Aebersold |
contact affiliation | Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zurich, Switzerland |
contact email | aebersold@imsb.biol.ethz.ch |
lab head | |
Alexander Schäfer |
contact affiliation | ETH Zurich |
contact email | schaefer@imsb.biol.ethz.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD012316
- Label: PRIDE project
- Name: Phosphoproteomics of endothelin signalling