PXD012201

PXD012201 is an original dataset announced via ProteomeXchange.

Title	Identification of PAC1 interactome in activated T cells
Description	To examine the molecular mechanisms by which PAC1 suppresses T cell response to antigen, we conducted immunoprecipitation followed by mass spectrometry to characterize PAC1-associated proteins in activated T cells
HostingRepository	PRIDE
AnnounceDate	2020-01-09
AnnouncementXML	Submission_2020-02-17_02:21:10.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liang Liu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-31 03:19:41	ID requested
1	2020-01-09 10:59:19	announced
2	2020-01-20 00:42:59	announced	2020-01-20: Updated publication reference for PubMed record(s): 31932812.
⏵ 3	2020-02-17 02:21:12	announced	2020-01-20: Updated publication reference for PubMed record(s): 31932812. 2020-02-17: Updated publication reference for PubMed record(s): 31932812.

Dan Lu, Liu L, Sun Y, Song J, Yin Q, Zhang G, Qi F, Hu Z, Yang Z, Zhou Z, Hu Y, Zhang L, Ji J, Zhao X, Jin Y, McNutt MA, Yin Y, The phosphatase PAC1 acts as a T cell suppressor and attenuates host antitumor immunity. Nat Immunol, 21(3):287-297(2020) [pubmed]

submitter keyword: PAC1, interactome, T cells

Yuxin Yin
contact affiliation	Peking University
contact email	yinyuxin@hsc.pku.edu.cn
lab head
Liang Liu
contact affiliation	Peking University
contact email	hsc_liuliang@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/01/PXD012201

PRIDE project URI

• PRIDE
  1. PXD012201
     1. Label: PRIDE project
     2. Name: Identification of PAC1 interactome in activated T cells