⮝ Full datasets listing

PXD012149

PXD012149 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSuccinylome analysis reveals the involvement of lysine succinylation in extreme resistance of Deinococcus radiodurans
DescriptionIncreasing evidences showing that succinylation of lysine residue mainly regulates enzymes involved in the carbon metabolism pathway, both in prokaryotic and eukaryotic cells. Deinococcus radiodurans is one of the most radioresistant organisms on earth, which is famous for its robust resistance. A major goal in the current study of protein succinylation is to explore its function in D. radiodurans. We used high-resolution liquid chromatography-mass spectrometry (LC-MS/MS) for qualitative proteomics to perform a global succinylation analysis of D. radiodurans and identified 492 succinylation sites on 270 proteins. These identified proteins are involved in a variety of biological process and pathways.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:21:24.884.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCongli Zhou
SpeciesList scientific name: Deinococcus radiodurans; NCBI TaxID: 1299;
ModificationListN6-succinyl-L-lysine
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-12-21 02:36:46ID requested
12021-04-25 21:34:12announced
22024-10-22 05:21:25announced2024-10-22: Updated project metadata.
Publication List
10.1002/pmic.201900158;
Zhou C, Dai J, Lu H, Chen Z, Guo M, He Y, Gao K, Ge T, Jin J, Wang L, Tian B, Hua Y, Zhao Y, Succinylome Analysis Reveals the Involvement of Lysine Succinylation in the Extreme Resistance of Deinococcus radiodurans. Proteomics, 19(20):e1900158(2019) [pubmed]
Keyword List
submitter keyword: succinylome
succinylation
DNA repair
Nucleic acid binding
posttranslational modification
Contact List
Ye Zhao
contact affiliationKey Laboratory of Chinese Ministry of Agriculture for Nuclear-Agricultural Sciences, Institute of Nuclear-Agricultural Sciences, Zhejiang University, China
contact emailyezhao@zju.edu.cn
lab head
Congli Zhou
contact affiliationZhejiang University
contact emailzhoucongli0628@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD012149
PRIDE project URI
Repository Record List
[ + ]