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PXD012147

PXD012147 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman macrophages in 3D - Macrophages are involved in a large number of tissue functions in homeostasis and various pathological situations
DescriptionMacrophages are involved in a large number of tissue functions in homeostasis and various pathological situations. These cells present a high degree of phenotypic plasticity that is grasped by the concept of polarization. One goal of the macrophage???s biology field is to obtain molecular signatures of these polarizations. To achieve this task, it is necessary to integrate how physical environment signals are interpreted by macrophages under immune stimulation. In this work, we have studied how a 3D collagen scaffold modulates the polarizations of human macrophages and revealed that some traditionally used markers should be reassessed.
HostingRepositoryPRIDE
AnnounceDate2020-03-12
AnnouncementXMLSubmission_2020-03-12_03:46:42.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterArnaud Millet
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListcarbamoylated residue; monohydroxylated residue; acetylated residue
InstrumentmaXis
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-12-21 01:59:51ID requested
12019-04-18 10:46:44announced
22020-03-12 03:46:44announced2020-03-12: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biological
submitter keyword: Human, macrophage, 3D, LC-MS/MS
Contact List
MILLET Arnaud
contact affiliationInserm IAB
contact emailarnaud.millet@inserm.fr
lab head
Arnaud Millet
contact affiliationInserm
contact emailarnaud.millet@inserm.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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