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PXD012145

PXD012145 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGSK3 alpha/beta knockout Mouse Podocytes proteomics
DescriptionThis is a set of proteomics performed on murine podocytes derived from a GSK3alpha/beta floxed mouse. GSK3 has been knocked down in the podocytes using lentiviral cre. This was performed 3 days prior to the analysis. For more details see paper entitled "Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function" published in Nature Communications.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:50:51.440.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRichard Coward
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-12-21 01:50:30ID requested
12019-11-14 03:48:51announced
22024-10-22 04:50:52announced2024-10-22: Updated project metadata.
Publication List
10.1038/s41467-018-08235-1;
Hurcombe JA, Hartley P, Lay AC, Ni L, Bedford JJ, Leader JP, Singh S, Murphy A, Scudamore CL, Marquez E, Barrington AF, Pinto V, Marchetti M, Wong LF, Uney J, Saleem MA, Mathieson PW, Patel S, Walker RJ, Woodgett JR, Quaggin SE, Welsh GI, Coward RJM, Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function. Nat Commun, 10(1):403(2019) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Mouse TMT proteomics
Contact List
Professor Richard Coward
contact affiliationBristol Renal University of Bristol UK
contact emailRichard.Coward@bristol.ac.uk
lab head
Richard Coward
contact affiliationUniversity of Bristol
contact emailRichard.Coward@bristol.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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