PXD012114

PXD012114 is an original dataset announced via ProteomeXchange.

Title	Human Hippocampus from Non-Hispanic Whites and African Americans with and without Alzheimer's disease LC-MS3
Description	This study examined global proteomic changes in postmortem hippocampus tissue from Non-Hispanic Whites and African American individuals who were cognitively normal or had Alzheimer's disease using LC-MS3 on an Orbitrap Fusion Lumos. Proteins were quantified in the LC-MS3 experiments using Tandem Mass Tags (TMT)10plex.
HostingRepository	PRIDE
AnnounceDate	2020-10-19
AnnouncementXML	Submission_2020-10-19_01:25:34.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kaitlyn Stepler
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-19 02:47:09	ID requested
⏵ 1	2020-10-19 01:25:34	announced

Stepler KE, Mahoney ER, Kofler J, Hohman TJ, Lopez OL, Robinson RAS, Inclusion of African American/Black adults in a pilot brain proteomics study of Alzheimer's disease. Neurobiol Dis, 146():105129(2020) [pubmed]

submitter keyword: Human, brain, hippocampus, LC-MS3, TMT

Renã A.S. Robinson
contact affiliation	Vanderbilt University Department of Chemistry
contact email	rena.as.robinson@vanderbilt.edu
lab head
Kaitlyn Stepler
contact affiliation	Vanderbilt University
contact email	kaitlyn.e.stepler@vanderbilt.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/10/PXD012114

PRIDE project URI

• PRIDE
  1. PXD012114
     1. Label: PRIDE project
     2. Name: Human Hippocampus from Non-Hispanic Whites and African Americans with and without Alzheimer's disease LC-MS3